Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The ACTG175 data can be obtained from the R package “speff2trial”. Supporting Information Filename Description sim70346-sup-0001-SupplementaryMaterial.pdfPDF document, 515.2 KB Data S1. Supporting Information. References 1, “Regression Models and Life Tables (With Discussion),” Journal of the Royal Statistical Society, Series B: Statistical Methodology 34 (1972): 187–220.