Liangyong Mei

Abstract Hsp40s, also termed J-domain proteins, play a central role in cellular protein homeostasis by promiscuously surveying the proteome for misfolded proteins. We have exploited this property to develop Hsp40 affinity profiling as a method for identifying proteins that misfold in response to cellular stresses. In this assay, we use the Hsp40 FlagDNAJB8H31Q as our recognition element for misfolded proteins.

Applications of Red Light Photoredox Catalysis in Organic Synthesis Abstract Photoredox catalysis has emerged as an efficient and versatile approach for developing novel synthetic methodologies. Particularly, red light photocatalysis catches more attention due to its intrinsic advantages of low energy, few health risks, few side reactions, and high penetration depth through various media. Impressive progress has been made in this field.

Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2020, 142, 28 RETURN TO ISSUEPREVCommunicationNEXT Liangyong Mei Liangyong Mei Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States , José M. Veleta José M. Veleta Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States , and Thomas L.