Liangzhen Hu

You are already at the latest version A new method for synthesis of various of 4-chloropyrazoles through the direct cyclization/chlorination of hydrazines by using 1,3,5-trichloroisocyanuric acid (TCCA) as both oxidant and chlorinating agent under mild conditions has been proposed. Based on the detailed optimization of the reaction conditions, the substrate generality has been investigated and the yields of the desired products is up to 92% .

Electrochemical synthesis of γ-keto sulfones containing β-quaternary carbon center via 1,2-migration An effective electrochemical rearrangement reaction, both oxidant and metal catalyst-free, is presented to construct γ-keto sulfones containing β-quaternary carbon center in the study. The protocol is produced by radicals generated from benzenesulfonyl hydrazines, which cause 1,2-migrations of starting materials 2-methylallyl alcohol derivatives and formation of new C-C and C-S bonds.

The copper(II)-promoted free radical oxidative difunctionalization of terminal alkenes to access ketoazides by utilizing molecular oxygen has been reported. A series of styrene derivatives have been evaluated and found to be compatible to give the desired difunctionalized product in moderate to good yields.