Lianhe Lu on Muck Rack

Lianhe Lu

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Proteomics-based machine learning model for predicting secondary infection in HBV-related liver failure - Nature Communications

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By Feixiang Xiong, Jianming Zheng, JiaJia Chen, Linhuan Wu, Yuyong Jiang, Tong Zhou, Yang Zhou, Tong Wu, Yamin Sun, Ronghua Jin, Yixin Hou, Lianhe Lu
| Nature
Abstract Patients with Hepatitis B Virus-related liver failure are highly vulnerable to secondary infections (SI), yet early predictive tools remain limited. In this work, we aim to develop and validate a plasma proteomics–based model for early SI risk assessment. In a prospective multicenter study, 114 patients are enrolled in the discovery cohort, 60 each in two validation cohorts.
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