Lianjin Liu on Muck Rack

Lianjin Liu

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A multi-center clinical trial of allogeneic hematopoietic stem cell transplantation in transfusion-dependent thalassemia - Nature Communications

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By Rongrong Liu, Hongwen Xiao, Chunjie Qin, Jiong Hu, Jianming Luo, Hong Chang Chen, Xi Zhang, Xiaolin Yin, Guanye Nai, Guyun Wang, Zan Li, Wei Tang, Hua Zhang, Xiaotao Wang, Mei Lan, Chuande Liao, Tonghua Yang, Sanbin Wang, Jinxiong Huang, Yunyan He, Li Wang, Zhongming Zhang, Lianjin Liu, Zhenbin Wei, Lingling Shi, Meiqing Wu, Qi Zhou, Borje S. Andersson, Xiaojun Huang, Yongrong Lai
| Nature Verified
Abstract Allogeneic stem cell transplantation (allo-HSCT) has recently been approved as standard therapy for transfusion-dependent thalassemia (TDT) but remains limited to the use of HLA-matched sibling donors (MSDs), due to a lack of large-scale prospective studies evaluating the use of grafts from alternative donors. Here, we report the results of a non-randomised, interventional, phase 4 clinical trial evaluating allo-HSCT from alternative donors for the treatment of TDT.
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