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Liat Bar-On on Muck Rack

Liat Bar-On

As seen in: Frontiers in Immunology
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Articles

The mRNA component of LNP-mRNA vaccines triggers IFNAR-dependent immune activation which attenuates the adaptive immune response

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By Hila Cohen, Uri Elia, Ofer Cohen, Noam Erez, Liat Bar-On, Lilach Cherry-Mimran
| Frontiers in Immunology
Introduction The development and licensure of mRNA vaccines against SARS-CoV-2 marked the beginning of a new era in vaccinology, offering a safe and versatile platform suitable for rapid mass production. These vaccines have demonstrated high efficacy, eliciting robust adaptive immune responses, characterized by elevated titers of neutralizing antibodies and the induction of antigen-specific CD4+ and CD8+ T cells (1–7).
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