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1 INTRODUCTION Miscarriage is a common early pregnancy complication that occurs in 15%–20% of all clinical pregnancies, and the majority occur in the first trimester.1, 2 The medical treatment of miscarriage is safe and less costly than surgical evacuation.3, 4 Vaginal misoprostol is recommended for the medical treatment of missed miscarriage by the clinical guideline published by the UK's National Institute for Health and Care Excellence (NICE).5 When used alone for the medical management of...
Materials and methods Study design and setting This non-inferiority, open-label randomised trial is conducted at the Department of Obstetrics and Gynaecology, The University of Hong Kong–Shenzhen Hospital, Shenzhen, China. Eligible women requesting medical management of missed miscarriage who are willing to participate are recruited.
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