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Libuse Janska

As seen in: PLOS Biology, BioRxiv
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Articles

Direct visualization of emergent metastatic features within an ex vivo model of the tumor microenvironment

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By Libi Anandi, Jeremy Garcia, Manon Steffan Ros, Libuse Janska
| BioRxiv
Abstract Metabolic conditions such as hypoxia, nutrient starvation, and media acidification, together with interactions with stromal cells are critical drivers of metastasis. Since these conditions arise deep within tumor tissues with poor access to the bloodstream, the observation of nascent metastases in vivo is exceedingly challenging. On the other hand, conventional cell culture studies cannot capture the complex nature of metastatic processes.
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Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects

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By Yevgeniy Plavskin, Humboldt-Universität zu Berlin, Naomi Ziv, Libuse Janska
| PLOS Biology Verified
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Plavskin Y, de Biase MS, Ziv N, Janská L, Zhu YO, Hall DW, et al. (2024) Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects. PLoS Biol 22(7): e3002698.
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Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects

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By Yevgeniy Plavskin, Naomi Ziv, Libuse Janska, Yuan O. Zhu
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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