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Liju Qian

As seen in: Nature
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Articles

Distinct neural substrates of obsessions and compulsions in adolescent obsessive compulsive disorder

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By Kun Li, Chenchen Zhang, Rui Li, Cong Zhou, Kexu Zhang, Wei Deng, Xiaochi Yuan, Liju Qian
| Nature Verified
Abstract Adolescent obsessive-compulsive disorder (OCD) is characterized by notable clinical heterogeneity, which may limit treatment precision. Although traditional content-based models have improved symptom characterization, they may overlook key pathophysiological features. A complementary process-based framework that distinguishes between obsessions and compulsions offers a promising alternative, but the neurobiological correlates of these dimensions remain poorly understood.
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