Lindsay Jane Morrison

1 INTRODUCTION Plexins are transmembrane proteins that serve as cell surface receptors for the axon guidance protein ligands, the semaphorins, in neuronal development, but they are also involved in many other cell migration processes that are part of angiogenesis, immune (Tran et al., 2007), bone, and other developmental processes (Buck, 2021; Kruger et al., 2005; Tran et al., 2007; Yazdani & Terman, 2006).

Cationic antimicrobial peptides (CAMPs) have known to act as multi-modal weapons against Gram-negative bacteria. As a new approach to investigate the nature of the interactions between CAMPs and the surfaces of bacteria, native mass spectrometry and two MS/MS strategies (ultraviolet photodissociation (UVPD) and higher energy collisional activation (HCD)) are used to examine formation and disassembly of saccharolipid/peptide complexes.