Line Pedersen
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Articles by Line Pedersen
«Vi er klare til å bidra. Er du?»
VOL - også kjent som Vesterålen Online og vol.no - holder til på Sortland og er en regionavis som dekker kommunene Andøy, Bø, Hadsel, Sortland og Øksnes.
What Can Providers' Motivations Tell Us About Healthcare Quality?
1 Introduction At their core, healthcare systems share the common goal of delivering high-quality care. However, evidence of providers' varying adherence to quality standards and clinical guidelines demonstrates the ongoing difficulties associated with successfully achieving this goal (Gandolfi et al. 2025). To respond to this challenge, policymakers use incentives to motivate providers to deliver high-quality care.
Induction of Yin Yang 1 (YY1) Overexpression in Mature Adipocytes Promotes Dysfunctional Adipose Tissue and Systemic Insulin Resistance in Mice
Publication Date 2-1-2026 DOI 10.1016/j.metabol.2025.156439 PubMedCentral® Posted Date 6-9-2026 PubMedCentral® Full Text Version Author MSS Abstract The ubiquitous transcription factor Ying Yang 1 (YY1) plays a fundamental role in multiple biological processes and is believed to regulate up to 10 % of all human genes.
Han frygtede ikke døden den nat i gården: Det var tanken om at se sin mor i øjnene der ændrede ham
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Her kæmper køreskoleeleverne mest i Silkeborgs trafik
Lorem ipsum dolor sit amet consectetur adipisicing elit. Illo reiciendis eos id iste. Tenetur, vel quam ullam illum reprehenderit doloremque vero incidunt dolorem eum excepturi est inventore molestiae, atque pariatur! Ocurreret voluptatum an has, aeque solet principes per in. Ei his platonem voluptatum, te vel fabulas ancillae, at mea justo paulo nonumes. Accumsan ponderum constituam sea eu, doctus dolorem scriptorem quo te. Nec diceret gloriatur moderatius id.
Leptin as a key driver for organ fibrogenesis
Abstract Leptin, a hormone primarily secreted by adipocytes, regulates energy balance and systemic metabolism through its interaction with the leptin receptor (LEPR). Beyond these functions, leptin signaling has been implicated in the pathogenesis of tissue fibrosis. Here, we report the x-ray crystal structures of a leptin-neutralizing antibody (hLep3) in the unbound and leptin-bound states.
Mean Opioid Use Estimates May Mask Different Longitudinal Use Patterns in Orthopaedic Populations: Group-Based Trajectory Modeling Is an Alternative
Keywords osteoarthritis knee arthroplasty opioids group-based trajectory modeling latent class growth analysis Opioid use before knee arthroplasty due to knee osteoarthritis (OA) is common [1–3], despite not being recommended in clinical guidelines [4]. Most studies investigating changes in opioid use in patients undergoing knee arthroplasty report overall group estimates, such as proportion of users or mean mg oral morphine equivalents (OMEQs) [1–3].
Et stort løft for Hadsel
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Meninger Vi er foreldre til noen av de hundrevis av barn og unge som vil få en helt ny hverdag innen både skole og fritid når hallen er klar om halvannet år. Vi vil, i likhet med politikerne som ble referert i lokalavisen, komme med all mulig skryt til jobben som er gjort. Vi ser at det fortsatt er noen som ikke kjenner prosjektet fullgodt, og refererer til det som en «gymsal». La oss feie all tvil til side: Dette handler om noe langt mer enn en gymsal.
By Bent Jakobsen, Camilla Fossheim, Caroline Henriksen, Daniel Ness, Daniel Olsen, Heidi Karlsen, Heidi Torkildson Ryste, Jeanette Dupont Jensen, Julie Hansen, Kjell Dyrset, Kristina Kristoffersen, Line Pedersen, Lisa Hansen, Lisa Wang, Maria Jakobsen, Marius Oustad Andreassen, Markus Lund, Mona Sørensen, Robin Sjøvoll, Siri Fagerholt Aas, Tom Lund, Trine Jakobsen, Vidar Pedersen, Vigleik Sjåvik, Anja Elen Eikenes, Ann Julie Reiertsen, Ann Karin Østeng, Ann Mari Løveng, Arlene Foster-Nielsen, Bjørnulf Jakobsen, Cathrine Hope Asbjørnsen, Christer Kjærvik, Christian Vatndal, Christoffer Olsen, Daniel Østeng, Eirik Sletten, Elise Robertsen Olsen, Eva Olstrøm Farstad, Fredrikke Johansen, Frida Vestgård, Gøran Jensen, Hannah Tomren Fredriksen, Helena Marie Amdal, Håkon Klausen, Ida R. Asbjørnsen, Ida Refnin, Ingvild Sørbø Kleppa, Iselin Hansen, Iselin Kiil, Janne Antonsen, Jens Molund, Joakim Antonsen, Jon-Ingar Kjelbergvik, Julie Freiberg, June Østeng, Jørgen Falstad Vindal, Kamila Szymanowska, Katarina Holst Moe, Katja Walle-Karlsen, Katrine Kristiansen, Kine Charlotte Holm, Knut Ivar Aarstein, Kristina Fyllingen Bråtveit, Lars Dragland, Lars Marcus Bekkevold, Larus Gudmundsson, Levin Kristoffersen, Linn Iren Haug, Lisa Knutsen, Lisbeth Falstad, Malin Falstad Vindal, Malin Gjerdrum, Malin Ødegård Kjelbergvik, Maria Elena Antonsen, Markus Fredriksen, Marte Andreassen, Martin André Rognstad, Martin Drageset, May-Liz Reinholdtsen, Mona Løveng, Monica Molund, Morten Endresen Vorhaug, Niklas Jørstad, Renate Kvandahl, Renate S. Tømmerås, Robin S. Tømmerås, Rune Bredal, Sara Margareta Eriksen, Silje Falstad, Silje Tømmerås, Sten Håvard Johannessen, Stine Valen, Svein-Roar Martinsen, Thomas Bentzen, Thomas Dahl Stokvik, Thomas Ebeltoft, Tor Erik Tendeland, Torbjørn Orrhaug, Vegard B. Fossheim, Veronica Bentzen, Vibeke Martinsen, Yngve Steinum Berg
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blv.no
Vedvarende bruk av høye doser opioider og andre vanedannende legemidler
Main findings Hovedfunn Antallet pasienter med et vedvarende bruk av høye doser opioider (definert som over to definerte døgndoser eller 50 mg orale morfinekvivalenter med opioider daglig i minst tre av fire kvartaler i løpet av året) var 7 010 (142 per 100 000 innbyggere) i 2011 og 12 199 (228 per 100 000 innbyggere) i 2019. Andelen av disse pasientene som fikk minst én av opioidreseptene på blå resept, var 31 % i 2011 og 51 % i 2019.
Acetic acid induces osmotic imbalances in drug-resistant bacteria synergistically enhancing cobalt-doped carbon quantum dots bactericidal efficiency
Abstract When pathogenic bacteria colonise a wound, they can create an alkaline ecological niche which selects for their survival by creating an inflammatory environment which restricts healthy wound healing to proceed. To aid healing, wound acidification has been exploited to disrupt this process and stimulate fibroblast growth, increase wound oxygen concentrations, minimise proteolytic activity and re-stimulate the host immune system.
Going the extra mile? General practitioners' upcoding of fees for home visits
1 INTRODUCTION General practitioners' (GPs') remuneration is often based on their self-reported activities or performances. As the payer cannot directly observe the GPs' effort (Arrow, 1986), GPs have an opportunity to ‘game the system’ to increase their income. One way of gaming the system is by misreporting diagnosis and procedure codes, also known as upcoding.
Adipose tissue fibrosis: the unwanted houseguest invited by obesity
Figure 1 Obesity-induced alterations in adipose tissue ECM composition. Summary of obesity-stimulated alterations in adipose tissue ECM composition and level of ECM remodelers compared to lean counterparts. Obesity increased ECM deposition as well as the presence of thicker and more aligned collagen fibers and ECM stiffness (Divoux et al. 2010, Mariman & Wang 2010). The levels of several MMPs and their inhibitors (TIMPs) are regulated in response to obesity (Lin et al. 2016).
Mapping GPs’ motivation - it’s not all about the money: a nationwide cross-sectional survey study from Denmark
Denmark general practice personnel retention prosocial motivation quality of care self-centred motivation INTRODUCTION Worldwide there is a physician shortage,1–3 and physicians’ wellbeing is being challenged.4–6 Literature reviews show that physicians’ wellbeing is associated with retention7–10 and quality of care;11,12 as such, a key to fostering physicians’ wellbeing may be to understand their work motivations.
Mapping GPs’ motivation - it’s not all about the money:
Denmark general practice personnel retention prosocial motivation quality of care self-centred motivation INTRODUCTION Worldwide there is a physician shortage,1–3 and physicians’ wellbeing is being challenged.4–6 Literature reviews show that physicians’ wellbeing is associated with retention7–10 and quality of care;11,12 as such, a key to fostering physicians’ wellbeing may be to understand their work motivations.
Mapping GPs’ motivation: it’s not all about the money; a nationwide cross-sectional survey study from Denmark
Denmark general practice personnel retention prosocial motivation quality of care self-centred motivation INTRODUCTION Worldwide there is a physician shortage,1–3 and physicians’ wellbeing is being challenged.4–6 Literature reviews show that physicians’ wellbeing is associated with retention7–10 and quality of care;11,12 as such, a key to fostering physicians’ wellbeing may be to understand their work motivations.
Sensory Interactions between Sweetness and Fat in a Chocolate Milk Beverage
Abstract : Fat and sugar-reduced foods and beverages have become increasingly popular for a variety of reasons, mainly relating to health and wellbeing. Depending on the food or beverage, it may be difficult to reduce the fat and/or sugar content and still maintain optimal sensory properties for the specific product. One way of approaching the problem is to gain a better understanding of how a product is affected by a reduction in fat and/or sugar.
Ukrainske Olga tør ikke sjekke nyheter fra hjemlandet
– Jeg opplever veldig mye frykt i hodet mitt. For folket, og for familien. Olga Gulbrandsen er på jobb i en matbod i Kristiansand. Det er ti år siden hun og ektemannen flyttet fra Ukraina til sørlandsbyen. Kontrastene fra et krigstruet Ukraina til fredelige Sørlandet er stor. Men nyhetene om konflikten i hjemlandet som stadig tikker inn fra forskjellige nettsteder, tenner frykten. Derfor skjermer hun seg mest mulig fra mobilen.
Aktiv i Konservative Folkeparti i Brønderslev: Det kan ikke passe, at lokalpolitik kun er for gamle mænd
Du skal være abonnent for at lytte til denne automatiske oplæsning. Prøv første måned for kun 1 kr. Køb abonnement Allerede abonnent? Login Følg os Andre tjenester At jeg er alene med to børn, synes at have været udslagsgivende for, at jeg ikke blev Konservatives spidskandidat i Brønderslev. Hvis det er rigtigt, har det alvorlige konsekvenser for ligestillingskampen i kommunalpolitik. Der er ikke oplæsning af denne artikel, så den oplæses derfor med maskinstemme.
Prognostic implications of left ventricular hypertrophy diagnosed on electrocardiogram vs echocardiography
Abstract It is unclear whether 12‐lead ECG employing standard criteria for left ventricular hypertrophy (LVH) provides similar information with respect to long‐term cardiovascular risk as echocardiography.
Golgi-Localized PAQR4 Mediates Antiapoptotic Ceramidase Activity in Breast Cancer
Metabolism and Chemical Biology Line Pedersen, Pouda Panahandeh, Muntequa I. Siraji, Stian Knappskog, Per Eystein Lønning, Ruth Gordillo, Philipp E. Scherer, Anders Molven, Knut Teigen and Nils Halberg DOI: 10.1158/0008-5472.CAN-19-3177 Published June 2020 This article requires a subscription to view the full text. You may purchase access to this article or login to access your subscription using the links below.
Golgi-localized PAQR4 mediates Anti-apoptotic Ceramidase Activity in Breast Cancer
Research Article Line Pedersen, Pouda Panahandeh, Muntequa I Siraji, Stian Knappskog, Per Eystein Lønning, Ruth Gordillo, Philipp E. Scherer, Anders Molven, Knut Teigen and Nils Halberg DOI: 10.1158/0008-5472.CAN-19-3177 Abstract The metabolic network of sphingolipids plays important roles in cancer biology. Prominent sphingolipids include ceramides and sphingosine-1-phosphate that regulate multiple aspects of growth, apoptosis, and cellular signaling.
Land-Use Planning In Denmark
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Retirement, job satisfaction and attitudes towards mandatory accreditation: a Danish survey study in general practice
A study on the attitudes of Danish GPs towards the forthcoming accreditation programme found that a total of 861 GPs (45%) had negative attitudes towards the programme, whereas 23% had positive attitudes. Older GPs, male GPs and GPs working in single-handed practices were more likely to be negative towards accreditation. As for regional differences, 54% of the respondents in the Region of Northern Denmark had negative attitudes compared with 43%–46% in the other regions.
Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and Redistribution
Highlights • Exercise reduces tumor incidence and growth in several mouse models • Exercise increases NK cell infiltration, thereby controlling tumor growth • Epinephrine mobilizes NK cells and β-blockade blunts the tumor suppression • Exercise-induced muscle-derived IL-6 is involved in NK cell redistribution Summary Regular exercise reduces the risk of cancer and disease recurrence. Yet the mechanisms behind this protection remain to be elucidated.
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