Introduction Gliomas, the predominant malignant neoplasms within the central nervous system, exhibit an incidence rate of approximately 6.61 per 100,000 individuals, representing a substantial majority of primary intracranial tumors.1 The WHO classification system delineates gliomas into low-grade (Grades I and II) and high-grade (Grades III and IV) categories.2 Notoriously characterized by their infiltrative and aggressive behavior, high-grade gliomas are marked by poor prognosis and limited...