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Lingkang Liu

As seen in: Frontiers
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Articles

Antibacterial effects of epigallocatechin gallate against calf diarrhea-causing Escherichia coli : in vitro and in vivo investigations

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By Yu Ren, Lingkang Liu, Wenya Zheng, Ben Liu, Zerui Zhao, Songlin Ding, Wei Hu, Lucheng Zheng, Hailong Hong, Xunhao Zhu, Lisen He, Qingcan Fan
| Frontiers
Abstract Introduction: Calf diarrhea caused by Escherichia coli poses severe economic burdens to the cattle industry, and antibiotic overuse has triggered drug resistance and residue risks. This study screened 10 plant extracts for antibacterial activity against a clinically isolated calf diarrhea-causing E. coli strain in vitro, and investigated the protective effects of epigallocatechin gallate (EGCG)—the most effective extract—on E. coli-infected mice.
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Frontiers | Listeria monocytogenes invasion in goat brain tissues: mechanisms of blood–brain barrier disruption and regulation of apoptosis and autophagy

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By Wenya Zheng, Ben Liu, Songlin Ding, Siyuan Shi, Yifan Wu, Yu Cao, Jingya Liu, Xiaojie Zhou, Xinli Huang, Yunhai Hu, Lingkang Liu
| Frontiers
Abstract Background: Listeria monocytogenes (LM), a zoonotic intracellular pathogen, causes fatal neurological infections in ruminants (e.g., goats) and humans. However, the mechanisms by which LM breaches the blood–brain barrier (BBB) and regulates neuronal programmed cell death (apoptosis/autophagy) remain unclear in caprine models—knowledge that is critical for livestock disease control.
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