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Lingtan Kong

As seen in: MDPI, ACS Publications
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Articles

Direct Targeting of Gene Regulators by Iridium(III) and Rhodium(III) Complexes

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By Lei Wu, Lingtan Kong, Wanhe Wang, Chung-Hang Leung
| dx.doi.org
Abstract Click to copy section linkSection link copied! Conspectus Aberrant gene expression is frequently linked to the progression of various disorders and diseases, playing an instrumental role in pathological processes. Gene-regulation-related proteins, especially epigenetic enzymes and transcription factors, are critically involved in gene expression patterns. Therefore, targeting endogenous gene regulators presents novel approaches for potential therapeutic intervention.
Open in Who Shared Issue with article?

Direct Targeting of Gene Regulators by Iridium(III) and Rhodium(III) Complexes

|
By Lei Wu, Lingtan Kong, Wanhe Wang, Chung-Hang Leung
| ACS Publications
Abstract Click to copy section linkSection link copied! Conspectus Aberrant gene expression is frequently linked to the progression of various disorders and diseases, playing an instrumental role in pathological processes. Gene-regulation-related proteins, especially epigenetic enzymes and transcription factors, are critically involved in gene expression patterns. Therefore, targeting endogenous gene regulators presents novel approaches for potential therapeutic intervention.
Open in Who Shared Issue with article?

Inhibiting Glycolysis and Disrupting the Mitochondrial HK2–VDAC1 Protein–Protein Interaction Using a Bifunctional Lonidamine-Conjugated Metal Probe for Combating Triple-Negative Breast Cancer

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By Ling Wang, Lingtan Kong, Liuqi Ye, Ding-Qi Zhang
| ACS Publications
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