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Articles by Lingyi Chen
Characterisation of the HLA-DPA1*01:194:01:02 Allele by Next-Generation Sequencing
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. References 1, , , et al., “The IPD-IMGT/HLA Database: Recent Developments in Sequence Submission,” Nucleic Acids Research 54 (2026): D1152–D1158.
Computer Science > Information Theory
Rate-distortion (RD) theory and its related formulations play a central role in understanding efficient information representation, but computing these quantities remains challenging in high-dimensional settings.
Mechanical characteristics and solidification mechanism of sodium silicate activated fly ash cement composite loess based fluidized stabilized materials
Abstract To address the practical engineering challenges of compaction difficulty and low efficiency associated with traditional backfilling methods for narrow and confined urban foundation trenches, this study proposes an eco-friendly backfill material: sodium silicate-activated fly ash-cement composite fluidized stabilized soil, using in-situ loess from the Xiong’an New Area as raw material. Material components were optimized through curing agent ratio determination and single-factor tests.
Response characteristic of bolt connection stress to jacking effect in prefabricated assembled utility tunnel in Xiong’an New Area, China
Abstract To reveal the mechanical response mechanism of bolted connections during the jacking construction of prefabricated utility tunnels, this study combines field monitoring and numerical simulation based on the utility tunnel project in Xiong’an New Area. The evolution characteristics and spatial distribution patterns of bolt stress are systematically investigated.
The role of TMEM59L in colorectal cancer progression and its interaction with the TGF-β/Smad pathway
Introduction Colorectal cancer (CRC) is one of the most common digestive system cancers worldwide, accounting for 10.0% of all cancer cases (1). As the burden of colorectal cancer increases, the identification of effective targeted therapy targets has become increasingly important. TMEM (Transmembrane proteins) are widely distributed proteins in cell membranes with multiple transmembrane domains.
ERK phosphorylates ESRRB to regulate the self-renewal and differentiation of mouse embryonic stem cells
Keywords ESRRB ERK embryonic stem cells self-renewal XEN differentiation Introduction Embryonic stem cells (ESCs) are pluripotent stem cells (PSCs) derived from the inner cell mass of the blastocyst (Evans and Kaufman, 1981; Martin, 1981). The indefinite in vitro self-renewal capacity and the differentiation potential into all cell types in the body, known as pluripotency, render ESCs as a promising source of donor cells for regenerative medicine.
mRMR-based wavelength selection for quantitative detection of Chinese yellow wine using NIRS
Wavelength selection plays an important role in the analysis of near-infrared(NIR) spectroscopy.This paper introduces the minimal-redundancy-maximal-relevance(mRMR) algorithm into NIR analysis for wavelength selection, by which relevance between spectrum and target component is maximized while redundancy among selected wavelengths is minimized. The wavelength selection method is applied in Chinese yellow wine to make prediction for concentration of ethanol.
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