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Linhui Ma

As seen in: Nature
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Articles by Linhui Ma

Behavioral outcomes after sevoflurane-based general anesthesia in preschool children: a prospective cohort study with perioperative hydrogen sulfide–related biomarker profiling

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By Zhichao Li, Youzhuang Zhu, Xuanyuan Pan, Shuai Li, Ruiying Fu, Jufang Shi, Linhui Ma, Qing Xu, Yanjing Li, Bo Zhang, Xueyan Liu, Qi Hou, Yuqing Wu, Jun Chai, Hui Zheng, Xiaobin Lyu
| Nature Verified
Abstract The association between general anesthesia (GA) for surgical procedures in preschool children and subsequent neurobehavioral outcomes remains unresolved, and human biomarker data on potential biological correlates are limited.
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Chronic alcohol exposure contributes to postoperative cognitive dysfunction via NR2B upregulation in the hippocampus of adult mice

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By Linhui Ma, Shuai Li, Wei Dong, Jie Wan, Zhichao Li, Chudi Zhang, Xinjie Zhou, Zhifan Wang, Chenghua Zhou, Yuqing Wu, Hui Zheng
| Nature Verified
Abstract Postoperative cognitive dysfunction (POCD) is a common perioperative complication of the central nervous system, and patients with chronic alcohol exposure frequently require surgery under anesthesia. However, the contribution of chronic alcohol exposure to POCD and its underlying mechanisms remains unclear. In this study, eight-week-old female and male mice were subjected to chronic alcohol exposure using the intermittent access two-bottle choice (IA2BC) paradigm.
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