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Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson’s disease-related fibril polymorphism | Acta Neuropathologica

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By Shaymaa Mohamed Mohamed, Higashiosaka City, Psychiatric Disorders, Lipidome Lab Co
| link.springer.com
Abstract Lipid interaction with α-synuclein (αSyn) has been long implicated in the pathogenesis of Parkinson’s disease (PD). However, it has not been fully determined which lipids are involved in the initiation of αSyn aggregation in PD.
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