NEWS AND VIEWS Why Anti–IL-17 Therapy Fails: The Role of Autonomous IL-17R Signaling in Autoimmune Inflammation Fabio S. Ryser, Corresponding Author Fabio S. Ryser Department of Rheumatology and Immunology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland Graduate School for Health Sciences, University Bern, Bern, Switzerland Correspondence: Fabio S.