While the technology is still early, Lilly is placing bets it can develop cancer vaccines using an mRNA approach, which targets encoded neoantigens that instruct the immune system to selectively attack cancer cells. The approach of therapeutic cancer vaccines has not been particularly successful in the past and the field has been marred by failures, as well as issues with toxicity.
Immunology is the largest therapeutic area under Johnson & Johnson’s pharmaceutical umbrella, with $3.6 billion in sales this quarter. But recent strategic decisions could hurt the future of the portfolio. J&J announced in its earnings statement Tuesday morning its decision to discontinue development of sirukumab in rheumatoid arthritis. The drug was knocked down by an advisory panel in August due to safety concerns and then outright rejected by the Food and Drug Administration in late September.
It wouldn’t take a report to see that M&A activity has ticked down after the boom years of 2014 and 2015, continuing last year's deceleration. But the analysis from Mergermarket, an M&A analysis firm, puts some hard numbers on that trend. In biotech and pharma, the two largest deals so far this year were the near $30 billion acquisition of European biotech Actelion Pharmaceuticals by Johnson & Johnson, and the $10.2 billion pick-up of CAR-T biotech Kite Pharma Inc by Gilead Sciences Inc.
Muck Rack makes it simple to find people, tweets, or articles that mention any name, keyword, company, hashtag etc. We've compiled this guide to help you make the most of your search.
Selecting a term
Start searching tweets, articles from media outlets, articles mentioned in tweets, journalists'
names, titles and bios with some suggested searches:
Companies or Topics (e.g. iPhone, Microsoft)
Phrases (e.g. "cloud computing") — use quotes to keep the terms together
Twitter handles (e.g. @username) — returns those who have mentioned or replied to
Names (e.g. "David Pogue")
Hashtags (e.g. #sxsw, #london2012)
Bio details (e.g. vegan, Olympics, father)
Muck Rack's Advanced Search allows for many boolean operators.
Find results that mention multiple specified terms, use AND or
+. For example, ensure each result contains both Elon Musk and Mark Zuckerberg by
searching Musk AND Zuckerberg or Musk + Zuckerberg.
Use the operators OR or , to broaden your search when you'd like either of
multiple terms to appear in results. (This is the default behavior of our search when no operators
are used). For example, results will contain either cake or cookie by searching cake OR cookie or cake,cookie
Use NOT or - to subtract results from your search. For
example, searching Disney will yield results about the Walt Disney Company as well as Walt Disney
World Resort. To exclude mentions of Disney World, search for Disney -World or Disney
When using one of these operators with a phrase, enclose it in quotation marks. For example, you can
find results about smartphones excluding Apple's iPhone 4S by searching smartphone -"iPhone
Exact case matching or punctuation
If you're searching for a brand name or keyword that relies on specific punctuation marks or capitalization, you can
find results that match your exact query by adding matchcase: before the keyword you're searching for, like matchcase:E*TRADE .
Use parentheses to separate multiple
boolean phrases. For example, to find journalists talking about having fun in Disney World or
Disneyland, search for ("disney world" OR disneyland) AND fun.
An asterisk can be used to search for any variation of a root word truncated by the asterisk. For example, searching for admin* will return results for administrator, administration, administer, administered, etc.
A near operator is an AND operator where you can control the distance between the words. You can vary the distance the near operation uses by adding a forward slash and number (between 0-99) such as strawberries NEAR/10 "whipped cream", which means the strawberries must exist within 10 words of "whipped cream".