Lisa Maria Koch on Muck Rack

Lisa Maria Koch

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Articles

Cytosolic pH regulates proliferation and tumour growth by promoting expression of cyclin D1

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By Stefanie Hiltbrunner, Lisa Maria Koch, Eivind Salmorin Birkeland, Alfredo J. Ibáñez
| Nature Verified
Abstract Enhanced growth and proliferation of cancer cells are accompanied by profound changes in cellular metabolism. These metabolic changes are also common under physiological conditions, and include increased glucose fermentation accompanied by elevated cytosolic pH (pHc)1,2. However, how these changes contribute to enhanced cell growth and proliferation is unclear.
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