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Lisabel Asuncion on Muck Rack

Lisabel Asuncion

As seen in: BioRxiv
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Articles

Prdm16 amplifies Notch signaling and suppresses venous lineage specification to prevent arteriovenous malformations during vascular development

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By Jore Van Wauwe, Sander Craps, Ashmita KC, Lisabel Asuncion
| BioRxiv
Abstract Proper arterial versus venous endothelial lineage identity is required to establish a hierarchical network of arteries and veins and prevent the occurrence of life-threatening arteriovenous malformations. The molecular mechanisms that govern arteriovenous lineage specification remain however incompletely understood.
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