Lisette Warkentin

Data sample Data captured between January 2012 and December 2017 were analysed (maximum 24 quarters). To analyse the onset of cascades, only data from patients with no prior history of thyroid examinations and/or thyroid disorder were selected. Data of patients who were 18 years or older and received a first thyroid stimulating hormone (TSH) test (as captured by the corresponding billing code) were included.

Baseline characteristics and unadjusted outcome rates After exclusions according to the predefined criteria, a total of 71 961 datasets were included in the analysis. The phenprocoumon cohort comprised 20 179 patients, the DOAC cohort 51 782 patients. The baseline characteristics are reported as proportion or mean with SD in table 1. The SMDs of the comparison of the phenprocoumon and DOAC cohorts before matching indicate differences between the groups in almost all variables.