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Articles

TRIM17 downregulation modulates CRPC progression and enzalutamide resistance by derepressing BCL2 expression via the p53-dependent and p53-independent pathways

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By Zhi Shang, Guowen Lin, LIU YU, Shiwei Liu, Yongqing Zhang, Zhe Hong, Dingwei Ye, Shengfeng Zheng, Zongyuan Hong
| Nature Verified
Abstract The failure of second-generation antiandrogen drugs such as enzalutamide (ENZ) treatment indicates that prostate cancer (PCa) can progress to castration-resistant prostate cancer (CRPC). CRPC is considered the terminal stage of PCa and currently has no effective treatment options due to drug resistance. However, the underlying mechanism of ENZ- resistance in CRPC remains unclear.
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El Pentágono ya no oculta sus guerras psicológicas

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By LIU YU
| Rebelion
Fuentes: Diario Tiempo Argentino Un cable diplomático firmado por el secretario de Estado Marco Rubio y filtrado por The Guardian el 30 de marzo de 2026, instruyó a todas las embajadas y consulados de Estados Unidos a lanzar campañas contra la propaganda extranjera, es decir, contra gran parte del mundo, desde la perspectiva del presidente Donald Trump. La directiva combinó el reclutamiento explícito de influencers, académicos y líderes comunitarios para que difundan mensajes favorables a EE.UU.
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Effects of different physical training models on physical preparation in school physical education

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By LIU YU, Tolegenuly Nurzhan
| Dialnet - Universidad de La Rioja
español Introducción: La preparación física es fundamental para la educación física escolar; sin embargo, existe heterogeneidad en la efectividad de los diferentes modelos de entrenamiento para la aptitud física de los adolescentes, con pocas comparaciones empíricas en entornos educativos reales.
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