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Liuhang Ren on Muck Rack

Liuhang Ren

As seen in: Frontiers
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Articles

Metabolomic signatures mediate the association between physical frailty and metabolic dysfunction-associated steatotic liver disease: a prospective cohort study

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By Doudou Li, Yacong Bo, Yao Chen, Zhitian Guo, Wenjie Zhang, Mingyi Xue, Yongjian Zhu, Tingting Li, Zhan Gao, Liuhang Ren
| Frontiers
Abstract Background: Physical frailty is linked to metabolic dysfunction-associated steatotic liver disease (MASLD), but the underlying metabolic mechanisms remain unclear. This study aimed to identify a frailty-related metabolic signature and examine its association with incident MASLD and its mediating role in the frailty-MASLD relationship. Methods: We analysed data from 244,187 UK Biobank participants. Frailty was assessed using the Fried Frailty Phenotype.
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