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Liyile Chen

As seen in: Nature, Wiley Online Library, MDPI
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Articles

Osteocyte-specific gasdermin D deletion accelerates osteoarthritis via promoting subchondral inflammation and remodeling

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By Yuki Ogawa, Taku Ebata, Liyile Chen, Ryota Suzuki, Tsutomu Endo, Hend Alhasan, Masanari Hamasaki, Daisuke Takahashi, Koji Iwasaki, Ken Kadoya, Tomohiro Onodera, Norimasa Iwasaki, M. Alaa Terkawi, Taiki Tokuhiro, Yuki Fujie, Masaya Nakajo
| Nature Verified
Abstract Subchondral bone remodeling in the early stages of osteoarthritis (OA) is characterized by elevated bone turnover and is closely associated with osteocyte function within the subchondral bone. However, beyond the canonical role of gasdermin D (GSDMD) in mediating pyroptosis in immune cells, its function in osteocytes remains poorly understood.
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Therapeutic Potential of Targeting Ferroptosis in Periprosthetic Osteolysis Induced by Ultra-High-Molecular-Weight Polyethylene Wear Debris

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By Takuya Ogawa, Shunichi Yokota, Liyile Chen, Yuki Ogawa
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Do Patients with Borderline Anemia Need Treatment before Total Hip Arthroplasty? A Propensity Score‐Matched Cohort Study

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By Lijun Cai, Chengcheng Zhao, Guangtao Han, Liyile Chen
| Wiley Online Library Verified
Introduction Preoperative anemia is extremely common in patients undergoing elective surgery.
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