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Liyin Chen

As seen in: Royal Society of Chemistry, BioRxiv, The American Journal of Human Genetics, medRxiv
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Articles

Visual Field-Guided Entangled Identifies Clinically Distinct Glaucoma Endophenotypes and Novel Risk Loci

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By Mousa Moradi, Liyin Chen, Yan Zhao
| medRxiv
The authors have declared no competing interest. This work was supported by National Institutes of Health (5R01EY036518). I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes The details of the IRB/oversight body that provided approval or exemption for the research described are given below: The Institutional Review Board at Mass General Brigham approved this retrospective study.
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Low population penetrance of variants associated with inherited retinal degenerations

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By Kirill Zaslavsky, Liyin Chen, Chloe M. Park, Emily M. Place, Seyedeh M Zekavat, Christopher Barile, Kinga M. Bujakowska, Elizabeth J. Rossin, Eric Pierce, Daniel Navarro-Gomez
| The American Journal of Human Genetics Verified
ArticleOnline nowOpen access 1Department of Ophthalmology and Vision Sciences, University of British Columbia, Vancouver, BC, Canada 2Ocular Genomics Institute, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA 3Harvard Medical School Department of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA 4The Broad Institute of Harvard and MIT, Cambridge, MA, USA Publication History: Received August 5, 2025; Accepted November 25, 2025; Published online December 22, 2025 DOI:...
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Causal Genomics in the Deep Learning Era

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By Liyin Chen
| preprints.org
You are already at the latest version Understanding the molecular causes of complex diseases remains one of the most pressing challenges in biomedicine. Despite large-scale genome-wide association studies (GWAS) mapping thousands of risk loci, identifying which genetic variants truly drive disease remains difficult.
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