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Identification and Analysis of Mitochondria‐Related Proteins in Haemophilic Arthritis Synovial Membranes Based on Proteomic Analysis
Haemophilic arthritis (HA), a severe complication in haemophiliacs, is driven by recurrent joint bleeding and iron overload from haemosiderin deposition, leading to synovial damage and joint dysfunction. Previous studies have examined the effects of iron overload on mitochondrial function, but the mechanisms linking iron metabolism disorders to mitochondrial dysfunction in HA remain poorly understood.
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