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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
MTPN drives noncanonical ERK hyperactivation in colorectal cancer and provides a promising therapeutic approach for precision medicine in CRC
Abstract Efforts to block the mitogen-activated protein kinase (MAPK) pathway for colorectal cancer (CRC) therapy are challenged by frequent oncogenic mutations of its upstream genes, robust extracellular signal-regulated kinase (ERK) reactivation and difficulty in tumor-selective targeting without compromising the physiological processes of normal cells. Deeper insight into the precise mechanism of ERK regulation could help develop potential therapeutic strategies.
Endoscopic surgery and temporalis muscle flap reconstruction for skull base osteoradionecrosis after radiotherapy
Abstract Introduction: Skull base osteoradionecrosis (sbORN) is a serious late complication of radiotherapy for nasopharyngeal carcinoma (NPC), with limited effective treatment options. In this retrospective cohort study, we aimed to compare the outcomes and treatment efficacy between patients with sbORN who did and those who did not undergo endoscopic extended resection with temporalis muscle flap reconstruction.
Understanding the Challenges of Readiness for Hospital Discharge in Stoma Patients: A Mixed‐Methods Study
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description jocn17654-sup-0001-Supinfo.docxWord 2007 document , 22.5 KB Data S1. jocn17654-sup-0002-AppendixS1.docxWord 2007 document , 16.2 KB Appendix S1. Interviewee characteristics. jocn17654-sup-0003-AppendixS2.docxWord 2007 document , 15.6 KB Appendix S2. Values assigned to dummy variables of categorical variables. References , , and . 2019.
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