Lohith Madireddy on Muck Rack

Lohith Madireddy

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Articles

A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

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By Lohith Madireddy, Nikolaos A. Patsopoulos, Chris Cotsapas, Steffan D Bos
| hal.science
A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis Mots clés Cellular signalling networks Genome informatics Genome-wide association studies Multiple sclerosis Origine : Publication financée par une institution Licence : CC BY - Paternité
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A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

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By Chris Cotsapas, Steffan D Bos, Lohith Madireddy, Niklaos A. Patsopoulos
| Nature Verified
Abstract Genome-wide association studies (GWAS) have identified more than 50,000 unique associations with common human traits. While this represents a substantial step forward, establishing the biology underlying these associations has proven extremely difficult. Even determining which cell types and which particular gene(s) are relevant continues to be a challenge.
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