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Long-jie Qu

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AZD1390, an ataxia telangiectasia mutated inhibitor, attenuates microglia‐mediated neuroinflammation and ischemic brain injury

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By Zhen Lan, Ying Liang, Long-jie Qu, Li-qiu Chen
| Wiley Online Library Verified
1 INTRODUCTION Stroke is the second-leading cause of death in the world and ischemic stroke accounts for the most part.1 The high mortality and the rate of disability threaten human health and quality of life. Currently, thrombolysis and endovascular thrombectomy have become the efficacious treatments of ischemic stroke, but the narrow therapeutic window and attendant risks hinder the clinical application. Therefore, more feasible and efficient therapy is pressing needed.
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