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Longest PW

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Articles

Inhaled formulation and device selection: bridging the gap between preclinical species and first-in-human studies

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By Byron PR, Delvadia RR, Longest PW, Jennifer L Wylie
| Bioanalysis Verified
The factors that influence inhaled first-in-human (FIH) device and formulation selection often differ significantly from the factors that have influenced the preceding preclinical experiments and inhalation toxicology work. In order to minimize the risk of delivery issues negatively impacting a respiratory pipeline program, the preclinical and FIH delivery systems must be considered holistically. This topic will be covered in more detail in this paper.
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