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Longtan Jiang

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Articles

A Non-Channel Function of CFTR: Attenuating Mitochondrial Oxidative Stress and Cardiomyocyte Senescence via Stabilization by USP45

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By Chun Liang Chen, Longtan Jiang, Yuewen Qiu
| Wiley Online Library Verified
1 Introduction Cardiomyocyte senescence is a critical risk factor for various cardiovascular diseases, including myocardial infarction, cardiac fibrosis, arrhythmia, heart failure, and atherosclerosis (Song et al. 2024). It can be triggered by multiple stressors such as DNA damage, oxidative stress, mitochondrial dysfunction, and epigenetic alterations (Zhang et al. 2024).
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