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Longyan Yin on Muck Rack

Longyan Yin

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Early-life sugar rationing, brain aging, and long-term neurodegenerative and psychiatric health outcomes: a population-based natural experiment study

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By Xingji Lian, Amei Chen, Xiaoyan Zhu, Yuyu Huang, Chongzhe Yang, Yan Huang, Bing Zhang, Meilong Ran, Longyan Yin
| Nature Verified
Abstract Early-life nutrition is linked to adult brain health, yet evidence from quasi-experimental studies remains scarce. Leveraging the UK’s historical sugar rationing as a natural experiment, we examined whether early-life sugar restriction reduces the risk of neurodegenerative and psychiatric disorders in later life. Among 60,394 UK Biobank participants (born 1951–1956), three groups were defined: in-utero-only, in utero plus 2 years, and non-rationed controls.
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