Lorenzo Breschi

1 Introduction Every so often, the introduction of a new material, technique, or technological innovation brings a paradigm shift in dental practice. Since the pioneering work of Buonocore, remarkable progress has been achieved in the field of adhesive dentistry [1]. One of the most significant milestones has been the development of reliable and long-lasting bonding agents for enamel and dentin substrates [2].

22 December 2025 OBJECTIVES A very uncommon kind of ameloblastoma that combines a traditional follicular or plexiform subtype with solid-type ameloblastoma and desmoplastic features is emerging as a distinct entity. Hybrid ameloblastoma is a rare and unique type of ameloblastoma—a benign but locally aggressive odontogenic tumor arising from the odontogenic epithelium, which is involved in the formation of teeth.

04 December 2025 Biomimetic has emerged as a multi-disciplinary science in several biomedical subjects in recent decades, including biomaterials and dentistry. In restorative dentistry, biomimetic approaches have been applied for a range of applications, such as restoring tooth defects using bioinspired peptides to achieve remineralization, bioactive and biomimetic biomaterials, and tissue engineering for regeneration.