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Lovise Gangeskar Paris

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Secretomes of Gingival Fibroblasts From Periodontally Diseased Tissues: A Proteomic Analysis

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By Niyaz Al-Sharabi, Einar K. Kristoffersen, Anne Kari Smedås, Lovise Gangeskar Paris
| Wiley Online Library Verified
1 Introduction Human gingival fibroblasts (GF) are a crucial component of the gingival stroma and have a significant role in the maintenance of periodontal tissue architecture and homeostasis (Wielento et al. 2023). Fibroblasts primarily synthesize the extracellular matrix (ECM), which consists of a variety of macromolecules whose assembly, architecture, and biomechanical properties vary within and between tissues (Plikus et al. 2021; McCulloch and Bordin 1991).
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