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Lucas Barwick on Muck Rack

Lucas Barwick

As seen in: BMC Genomics
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Computational deconvolution of cell type-specific gene expression in COPD and IPF lungs reveals disease severity associations - BMC Genomics

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By Min Hyung Ryu, Jeong Yun, Kangjin Kim, Michele Gentili, Auyon J Ghosh, Frank C. Sciurba, Andrew H Limper, Gerard J. Criner, Kevin Brown, Robert Wise, Fernando Martinez, Fernando Martínez, Kevin Flaherty, Michael Cho, Peter J Castaldi, Lucas Barwick
| BMC Genomics
465 subjects met the case criteria for COPD, 213 subjects met the case criteria for IPF, and 348 subjects met the control criteria. Demographic and clinical characteristics of the 1,026 subjects included in our analysis are shown in Table 1. Notably, IPF subjects were predominantly male (70%). The cohort included 90% of self-identified white subjects. COPD subjects were predominantly smokers (95.2% have ever smoked) and IPF and control subjects were 65.3% and 67.8% ever smokers, respectively.
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