Lucia Adeva Contreras on Muck Rack

Lucia Adeva Contreras

As seen in: Dialnet - Universidad de La Rioja
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The impact of high altitude (hypobaric hypoxia) on insulin resistance in humans

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By Magdalena Adeva Andany, Natália Carneiro, Lucia Adeva Contreras
| Dialnet - Universidad de La Rioja
Exposure to hypobaric hypoxia (high altitude) diminishes systemic tissue oxygenation. Tissue hypoxia induces insulin resistance and a metabolic switch that reduces oxidative phosphorylation and glucose storage while enhancing glycolysis. Similarly to hypobaric hypoxia, insulin resistance develops in normal humans undergoing normobaric hypoxia and in patients with obstructive sleep apnea.
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