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Lucrezia Maria Ribolla on Muck Rack

Lucrezia Maria Ribolla

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Articles

Altering the biophysical properties of ERC1/ELKS–driven condensates interferes with cell motility - Communications Biology

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By Massimo Degano, Lucrezia Maria Ribolla, Marco Patrone
| Nature Verified
Abstract Cell migration is orchestrated by molecular networks supporting motility. The scaffolds ERC1/ELKS and Liprin-α1 sustain cell migration and invasion by assembling dynamic plasma membrane-associated platforms. ERC1/ELKS forms cytoplasmic condensates with liquid–like behavior. In this study we tested whether the ability of ERC1 to form condensates is relevant to its function in cell motility.
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