Luigi Bartalena

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Graves' orbitopathy, which affects about 25–30% of newly diagnosed patients with hyperthyroidism due to Graves' disease, 1 Tanda ML Piantanida E Liparulo L et al. Prevalence and natural history of Graves' orbitopathy in a large series of patients with newly diagnosed Graves' hyperthyroidism seen at a single center. J Clin Endocrinol Metab.

Additionally, Graves' disease is also associated with extrathyroidal manifestations, especially Graves' orbitopathy—a life-changing and disfiguring disease of the eyes—the course of which is influenced by thyroid dysfunction. 2 Bartalena L Baldeschi L Boboridis K et al. The 2016 European Thyroid Association/European Group on Graves' Orbitopathy for the management of Graves' orbitopathy. Eur Thyroid J.