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Luis Martin Pena on Muck Rack

Luis Martin Pena

As seen in: BioRxiv
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Articles

A robust workflow to benchmark deconvolution of multi-omic data

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By Slim Karkar, Elise Amblard, Vadim Bertrand, Luis Martin Pena
| BioRxiv
Abstract Tumour heterogeneity significantly affects cancer progression and therapeutic response, yet quantifying it from bulk molecular data remains challenging. Deconvolution algorithms, which estimate cell-type proportions in bulk samples, offer a potential solution. However, there is no consensus on the optimal algorithm for transcriptomic or methylomic data.
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