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Lukas Scheller

As seen in: Cell Press
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Articles by Lukas Scheller

A longitudinal single-cell atlas to predict outcome and toxicity after BCMA-directed CAR T cell therapy in multiple myeloma

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By Michael Rade, David Fandrei, Markus Kreuz, Sabine Seiffert, Anja Grahnert, Maik Friedrich, Thomas C. Wiemers, Patrick Born, Luise Fischer, Heike Weidner, Lorenz C. Hofbauer, Ronny Baber, Song Wang, Enrica Bach, Sandra Hoffmann, Jonathan Scolnick, Mirco Friedrich, Farid Keramati, Peter Brazda, Zsolt Sebestyen, Jürgen Kuball, Miriam Alb, Lukas Scheller, Michael Hudecek, Hermann Einsele, Klaus H. Metzeler, Marco Herling, Carmen Diana Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Andreas Boldt, Ulrike Kohl, Uwe Platzbecker, Vladan Vucinic, Kristin Reiche, Maximilian Merz
| Cell Press Verified
Results We recruited a real-world cohort of 61 RRMM patients treated with BCMA-directed CAR T cells at our center. Samples of 57 patients were available for single-cell multi-omics profiling: A total of 135 peripheral blood mononuclear cell (PBMC) samples at 3 different time points were collected for single cell RNA, B cell receptor (BCR), TCR and surface protein profiling.
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Visualization of Activated T Cells by OX40-ImmunoPET as a Strategy for Diagnosis of Acute Graft-versus-Host Disease

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By Israt S. Alam, Federico Simonetta, Lukas Scheller, Aaron T Mayer
| cancerres.aacrjournals.org
Tumor Biology and Immunology Israt S. Alam, Federico Simonetta, Lukas Scheller, Aaron T. Mayer, Surya Murty, Ophir Vermesh, Tomomi W. Nobashi, Juliane K. Lohmeyer, Toshihito Hirai, Jeanette Baker, Kenneth H. Lau, Robert Negrin and Sanjiv S.
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Visualization of activated T cells by OX40-immunoPET as a strategy for diagnosis of acute Graft-versus-Host-Disease

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By Israt S. Alam, Federico Simonetta, Aaron T Mayer, Lukas Scheller
| cancerres.aacrjournals.org
Research Article Israt S Alam, Federico Simonetta, Lukas Scheller, Aaron T Mayer, Surya Murty, Ophir Vermesh, Tomomi W Nobashi, Juliane K Lohmeyer, Toshihito Hirai, Jeanette Baker, Kenneth H Lau, Robert Negrin and Sanjiv S. Gambhir DOI: 10.1158/0008-5472.CAN-20-1149 Abstract Graft versus host disease (GvHD) is a major complication of allogeneic hematopoietic cell transplantation (HCT), mediated primarily by donor T cells that become activated and attack host tissues.
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