Lukas Schulte

1 INTRODUCTION Adenoviruses (Ad) are non-enveloped double-stranded DNA viruses for which the linear genomes comprise between 26 and 45kb.1 There are currently 113 known Ad serotypes infecting humans.2 In immunocompetent hosts, they usually cause mild or asymptomatic infections of the respiratory tract, the digestive tract or the eye.3 Serotypes differ notably in their clinical presentation and in their tropism, partly because of differences in the knob domain of the fiber protein, which is...