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Systematic spatio-temporal mapping reveals divergent cell death pathways in three mouse models of hereditary retinal degeneration

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By Michael Power Verified, Timm Schubert, Philipp Berens, Luke Edward Rogerson
| BioRxiv
New Results Michael J Power, Luke Edward Rogerson, Timm Schubert, Philipp Berens, Thomas Euler, Francois Paquet-Durand doi: https://doi.org/10.1101/554733 Abstract Calcium (Ca2+) dysregulation has been linked to neuronal cell death, including in hereditary retinal degeneration. Ca2+ dysregulation is thought to cause rod and cone photoreceptor cell death. Validation of this hypothesis has been hampered so far by spatial and temporal heterogeneities in retinal disease models.
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