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Abstract Response to intravesical Bacillus Calmette-Guérin (BCG) varies among patients with intermediate/high-risk non-muscle-invasive bladder cancer (NMIBC). We investigated whether tumor-infiltrating memory B cells (MBCs) and tertiary lymphoid structures (TLSs) are associated with BCG response. RNA-sequencing data from GSE176178 served as the discovery cohort for identifying immune-cell subsets associated with BCG response via CIBERSORT deconvolution.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
