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Ying-ang Ji on Muck Rack

Ying-ang Ji

As seen in: Nature, Frontiers in Immunology
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Articles

Memory B cells in mature follicle-like tertiary lymphoid structures predict BCG response in non-muscle-invasive bladder cancer

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By Haitao Wang, Ying-ang Ji, Weiming Luo, Yangkun Ao, Jian Zhang, Yapeng Wang, Qiang Ran, Junying Zhang, Jing Xu, Jun Zhang, Jun Jiang, Qiuli Liu, Weihua Lan, Qiubo Xie, Luofu Wang
| Nature Verified
Abstract Response to intravesical Bacillus Calmette-Guérin (BCG) varies among patients with intermediate/high-risk non-muscle-invasive bladder cancer (NMIBC). We investigated whether tumor-infiltrating memory B cells (MBCs) and tertiary lymphoid structures (TLSs) are associated with BCG response. RNA-sequencing data from GSE176178 served as the discovery cohort for identifying immune-cell subsets associated with BCG response via CIBERSORT deconvolution.
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SWI/SNF complex alterations predict immunotherapy response in bladder cancer

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By Jian Zhang, Yapeng Wang, Qian Yan, Haitao Wang, Qiang Ran, Hailin Zhu, Weiming Luo, Jing Xu, Jun Zhang, Yao Zhang, Jun Jiang, Qiuli Liu, Weihua Lan, Yangkun Ao, Ying-ang Ji
| Frontiers in Immunology
1 Introduction Bladder cancer represents the fourth most prevalent malignancy among men worldwide, ranking ninth in global incidence and thirteenth in mortality (1). Pathologically, most cases are urothelial carcinoma, clinically stratified into non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) disease based on depth of invasion.
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