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Luojie Deng on Muck Rack

Luojie Deng

As seen in: Frontiers
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Articles

Rapid postoperative platelet decline in a lung adenocarcinoma with sarcomatoid differentiation and concomitant JAK2 V617F mutation: a case report

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By Xiaoping Li, Luojie Deng
| Frontiers
CASE REPORT article Volume 15 - 2025 | https://doi.org/10.3389/fonc.2025.1722712 Introduction Reactive thrombocytosis in solid tumors is typically mediated by IL-6-driven thrombopoietin production. While JAK2 V617F mutation is well-established in myeloproliferative neoplasms (>95% polycythemia vera), its occurrence in non-hematopoietic malignancies is exceptionally rare. However, the biological significance of concurrent JAK2/TP53/MET alterations in NSCLC remains unexplored.
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