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Association of cumulative cholesterol-HDL-glucose index with cardiovascular disease risk in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide prospective cohort study
Abstract Cardiovascular–kidney–metabolic (CKM) syndrome integrates cardiovascular disease, chronic kidney disease, and metabolic risk factors, highlighting their interaction and shared progression. The cholesterol–HDL–glucose (CHG) index is a composite lipid–glucose index that may reflect metabolic dysfunction related to insulin resistance, although it is not a direct measure of insulin sensitivity.
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