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Articles

Five Years On: Assessing Governance, Stability and Foreign Relations under Taliban Rule

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By LUTFUR RAHMAN
| ips.org.pk
Five Years On: Assessing Governance, Stability and Foreign Relations under Taliban Rule IPSweb International Relations, Pakistan and its Neighbours, Policy Insights, Research Prepared By: Dr Lutfur Rahman Like: 0 This analysis by Dr Lutfur Rahman, Senior Research Fellow at IPS, assesses five years of Taliban rule in Afghanistan from academic perspective, examining the balance between relative security gains and the country’s continuing domestic and regional challenges.
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Nintedanib inhibits the VEGFR–ERK signaling pathway in human KRAS -mutated cancer cells

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By Sivasundaram Karnan, Akinobu Ota, Muhammad Hasan, Toshinori Hyodo, Nushrat Jahan, Hideki Murakami, Ichiro Hanamura, Lâm Vũ, Miho Riku, Hideaki Ito, Yoshifumi Kaneko, Yinzhi Lin, LUTFUR RAHMAN, Shingo Inaguma, Takuya Matsui, Hiroyuki Konishi, Shinobu Tsuzuki, Yoshitaka Hosokawa
| Nature Verified
Abstract KRAS mutations are significant drivers in various cancers, and existing drug discovery attempts targeting these mutations have largely been unsuccessful, emphasizing the need for more effective therapies. In this study, the screening library, which contains 1,374 chemical compounds, identified nintedanib, a VEGFR inhibitor, as exerting a potent and selective antiproliferative effect against KRAS-mutant cells, surpassing other VEGFR inhibitors.
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Ecofriendly synthesis and characterization of copper chitosan nanoparticles (CuChNPs) and assessing combined effect of nanoparticles and bismerthiozol against bacterial leaf blight of rice

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By Rumana Akter, LUTFUR RAHMAN, Omar Kayess, Rakibul Hasan, Mohammad Abdul Latif, A. K. M. Sahfiqul Islam
| Nature Verified
Abstract The rice bacterial blight pathogen, Xanthomonas oryzae pv. oryzae (Xoo), poses a major threat to global rice production. While chitosan and copper-based nanoparticles have been explored for plant disease control, their potential to function as synergistic boosters for reducing conventional agrochemical dosage remains largely underexploited.
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