Luvna Dhawka on Muck Rack

Luvna Dhawka

As seen in: Nature, MDPI
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Articles

Leveraging Single-Cell RNA-Seq to Generate Robust Microglia Aging Clocks

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By Natalie Stanley, Luvna Dhawka, Yu-Chen Huang, Sneha Jaikumar
| biorxiv.org
Abstract 'Biological aging clocks' - composite molecular markers thought to capture an individual's biological age - have been traditionally developed through bulk-level analyses of mixed cells and tissues. However, recent evidence highlights the importance of gaining single-cell-level insights into the aging process. Microglia are key immune cells in the brain shown to adapt functionally in aging and disease.
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Post-ischemic ubiquitination at the postsynaptic density reversibly influences the activity of ischemia-relevant kinases - Communications Biology

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By Luvna Dhawka, Emma Hambright, Sheng Zhang, Costantino Iadecola
| Nature Verified
Abstract Ubiquitin modifications alter protein function and stability, thereby regulating cell homeostasis and viability, particularly under stress. Ischemic stroke induces protein ubiquitination at the ischemic periphery, wherein cells remain viable, however the identity of ubiquitinated proteins is unknown. Here, we employed a proteomics approach to identify these proteins in mice undergoing ischemic stroke.
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Risk for Seasonal Affective Disorder (SAD) Linked to Circadian Clock Gene Variants

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By Thanh Dang, William Russel, Luvna Dhawka, Tazmilur Saad
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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