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Articles

Cell Probe Cocktail Enables Ratiometric miRNA Detection with Enhanced Sensitivity and an Extended Dynamic Range Click to copy article link Article link copied!

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By Shengkai Zhang, Lanshuang Hu, Luyin Wang
| dx.doi.org
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Fluid Multivalent Recognition Accelerating and Boosting Upconversion Luminescence-Activated DNA Nanomachines for Rapid and Sensitive In Vivo Imaging

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By Liuyan Zhou, Xiaokun Li, Zhihong Zhou, Luyin Wang
| dx.doi.org
By integrating near-infrared (NIR) light-dependent optical control and DNA walkers-based signal amplification, upconversion luminescence-activated DNA nanomachines hold great potential in conducting an in vivo analysis. For the typical DNA nanomachines, the immobile multivalent recognition interface greatly compromised the reaction kinetics and amplification efficiency due to the cleavage-dependent response mode.
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